Best Weed Strains for Depression


Best Weed Strains for Depression

What is depression? What are the best weed strains for depression in Washington, D.C.? Depression, or major depressive disorder, is a mental health condition that impacts how a person feels and interacts with others. Depression can cause sadness, isolation, and loss of interest in what a person once enjoyed. Statistics indicate that the number of U.S. adults diagnosed with depression is rising. At least 29 percent of American adults have been diagnosed with depression at some point in their lifetime.

Depression treatment may include a combination of medication and psychotherapy. However, finding the right combination of mental health intervention and medication can feel overwhelming. An individual’s unique brain chemistry can make treating depression with medication challenging. Often, it takes months for the full benefits of prescription medication to take effect. Still, many healthcare professionals must closely monitor patients and change dosing to reduce unwanted side effects and strike the proper chemical balance.

An increasing body of evidence now shows that cannabis may help relieve the symptoms of depression and provide positive long-term effects in many people diagnosed with the condition.

How Weed Helps Depression

Some studies indicate that people diagnosed with depression may benefit from cannabis therapy to treat and manage their mental health conditions. Research shows that those diagnosed with clinical depression who use cannabis had lower depression scores than those who are not cannabis users. In the study, those diagnosed with depression who used medicinal cannabis reported better sleep, less pain, less anxiety, and a higher quality of life than those who did not use cannabis. Strains exceptionally high in the compound CBD offered individuals the most improvement.

Cannabis plants contain hundreds of unique compounds and cannabinoids that may impact the human body in various ways. Many of these compounds still need to be thoroughly studied. However, a growing body of medical evidence suggests that the unique compounds in cannabis plants may play a vital role in regulating mood and buffering stress response by interacting with the body’s endocannabinoid system. Specific compounds may bind to CB1 receptors, helping to regulate depressive behaviors and offering antidepressant-like effects.

Best Weed Strains for Depression

A variety of strains may be useful for treating depression. If you’re considering cannabis therapy to manage depression, it’s crucial to choose the right strains that can potentially provide relief. Here are some of the best weed strains for depression:

Sour OG

Sour OG is a hybrid cannabis strain that offers a balanced experience. It is high in stimulating terpenes like beta-caryophyllene, which may trigger anti-depressant-like effects. Its flavor profile offers notes of pine and sour lemon.

Granddaddy Purple 

Granddaddy Purple is an Indica-dominant strain with a complex grape and berry flavor profile. Terpenes like myrcene and pinene have calming effects on the mind and body and may ease the symptoms of depression and anxiety.


XJ-13 is a Sativa-dominant strain with high levels of the compound THC. It can produce euphoric effects and help relieve stress and mood-related symptoms associated with depression and anxiety. It has a strong citrus flavor with undertones of pine and is one of the leading strains for those suffering from depression.

Jack Herrer 

Jack Herrer is another sativa-dominant cannabis strain known for activating the mind and stimulating the senses. It has an energizing effect and can help individuals enhance creativity and focus. Many categorize the strain as spicy with hints of pine.

Blue Dream 

Blue Dream is also a sativa-forward strain that produces a more balanced “high” that stimulates the brain while relaxing the body. It is often used to treat symptoms of depression, ease anxiety, and create a positive mood. Those with chronic pain may also like this strain because it can ease migraines and muscle spasms.


Prism offers individuals an uplifting, euphoric experience because it is a sativa-dominant cannabis strain. It can enhance mental clarity, creativity, and mood while promoting peace. It is popular for individuals with depression, anxiety, and chronic pain.

Types of Mood Disorders that These Strains Can Help

Depression, or depressive disorder, is a distinct diagnosis. However, depression is sometimes an umbrella term for many mental health conditions and disorders. The therapeutic benefits of cannabis may help ease the symptoms of numerous mental health and mood disorders, including:

  • Depression
  • Anxiety
  • Post-traumatic stress disorder
  • Mania

Before adding cannabis to your mental health routine and deciding on the best strains for mood disorders, talk to your doctor. In some patients, cannabis consumption can trigger feelings of paranoia or increase the symptoms of depression. Cannabis may also interact with other types of drugs and medications. A healthcare professional can evaluate your unique situation and assess the benefits and risks of adding cannabis to your medication lineup.

Indica, Sativa, or Hybrid: Which is Best for Depression?

Best Weed Strains for Depression 2Today, there are more than one thousand unique cannabis strains. Choosing the right product to manage your mental health condition can be challenging, especially when you don’t understand the difference between the two main types of cannabis plants. There are two distinct cannabis strains: indica and sativa. Indica plants come from the harsh, dry climates of Afghanistan, India, Turkey, and Pakistan along the Hindu Kush mountain range. Indica plants are typically short and stocky but are fast-growing. These plants often produce numerous buds and have higher levels of CBD than THC. Indica plants and indica-dominant hybrid strains are known for their calming effects. While they are best suited for evening use and to promote relaxation, some indica strains may intensify depression symptoms.

Sativa plants are native to the hot, dry areas of Africa, Central America, and Southwest Asia. These plants are taller and thinner than indica plants and take longer to reach maturity. Sativa cannabis tends to have lower CBD and higher concentrations of THC, producing euphoria and energizing. Most people use sativa and sativa-dominant plants during the day because of the plant’s stimulating effects. These plants best suit those seeking mental clarity, creativity, and anxiety-reducing effects.

Hybrid cannabis plants have unique characteristics of both indica and sativa. The effects of a hybrid strain depend on the characteristics of each parent plant. Sativa-dominant hybrid strains work well for patients with mood disorders because they combine the energizing and mood-elevating effects of sativa plants with some of the relaxing elements present in indica strains.  

Utilize Fast Slice to Get Depression-Easing Cannabis in Washington, D.C.

At Fast Slice, we understand that choosing the right cannabis strains to manage depression can be challenging. That’s why we offer a carefully curated selection of the best weed strains that may help with depression and address your unique needs and mental health concerns. Our cannabis products are high-quality and easily accessible by delivery or pick-up. From flower to edibles, we have finely curated selections of premium cannabis that we discreetly deliver to your door. Explore our cannabis selection today, and let us help you pick the products best suited to your needs. Please don’t hesitate to connect with us for any questions you may have regarding our cannabis products.

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